Connection | Profiles RNS

Search Result Details

Back to Search Results

This page shows the details of why an item matched the keywords from your search.

Search Results

MCDONNELL, DONALD

One or more keywords matched the following items that are connected to MCDONNELL, DONALD

Item Type	Name
Academic Article	Elucidation of the molecular mechanism of action of selective estrogen receptor modulators.
Academic Article	The molecular determinants of estrogen receptor pharmacology.
Academic Article	Definition of the molecular and cellular mechanisms underlying the tissue-selective agonist/antagonist activities of selective estrogen receptor modulators.
Academic Article	27-hydroxycholesterol is an endogenous selective estrogen receptor modulator.
Academic Article	The endogenous selective estrogen receptor modulator 27-hydroxycholesterol is a negative regulator of bone homeostasis.
Academic Article	Mechanism-based discovery as an approach to identify the next generation of estrogen receptor modulators.
Academic Article	The molecular mechanisms underlying the pharmacological actions of estrogens, SERMs and oxysterols: implications for the treatment and prevention of osteoporosis.
Academic Article	27-Hydroxycholesterol: a potential endogenous regulator of estrogen receptor signaling.
Academic Article	The molecular mechanisms underlying the pharmacological actions of ER modulators: implications for new drug discovery in breast cancer.
Academic Article	Mining the complexities of the estrogen signaling pathways for novel therapeutics.
Academic Article	Structural basis for an unexpected mode of SERM-mediated ER antagonism.
Academic Article	Coregulators in nuclear estrogen receptor action: from concept to therapeutic targeting.
Academic Article	Regulation of aryl hydrocarbon receptor function by selective estrogen receptor modulators.
Academic Article	Research resource: Transcriptional profiling in a cellular model of breast cancer reveals functional and mechanistic differences between clinically relevant SERM and between SERM/estrogen complexes.
Concept	Selective Estrogen Receptor Modulators
Academic Article	From empirical to mechanism-based discovery of clinically useful Selective Estrogen Receptor Modulators (SERMs).
Academic Article	Efficacy of SERD/SERM Hybrid-CDK4/6 Inhibitor Combinations in Models of Endocrine Therapy-Resistant Breast Cancer.
Academic Article	Oral Selective Estrogen Receptor Downregulators (SERDs), a Breakthrough Endocrine Therapy for Breast Cancer.
Academic Article	Evaluation of the pharmacological activities of RAD1901, a selective estrogen receptor degrader.
Academic Article	Targeting mutant estrogen receptors.
Grant	Mechanism of Action of Estrogens and Antiestrogens
Academic Article	Constitutively active ESR1 mutations in gynecologic malignancies and clinical response to estrogen-receptor directed therapies.
Academic Article	The Dysregulated Pharmacology of Clinically Relevant ESR1 Mutants is Normalized by Ligand-activated WT Receptor.
Academic Article	Next-Generation Endocrine Therapies for Breast Cancer.
Academic Article	Current and emerging estrogen receptor-targeted therapies for the treatment of breast cancer.
Academic Article	Estrogen Receptor Signaling in the Immune System.

Search Criteria

Selective Estrogen Receptor Modulators